176 COVID-19 disease and cardiac involvement – a local experience

Aims The aim of this review to assess cardiac involvement in patients with severe COVID-19 patients. We all COVID 19 disease admitted our trust requiring transthoracic echocardiograms on their clinical indications. Background Cardiac has been found be prognostic factor and related higher mortality morbidity. In a large series those heart had fatality rate around 10.5%.1 2 Methods All adult who were positive PCR between March 2020 February 2021, an echocardiogram, identified through local database. Their demographics, co-morbid, troponin levels Pro NT-BNP analysed. reports which finalised by the imaging cardiologist included analysis. Results There total 41 during stay hospital disease. Mean age was 70 (range 45-90) years old. 70% male 30% female 12% diabetic, 49% hypertensive 40% previous Pulmonary embolism diagnosed 10% CT pulmonary angiogram. 56% required high flow oxygen 21% need mechanical ventilation. Almost CRP admission. level 215 mean 197. D dimer 1130, creatinine 138. 92% evidence lung chest X-ray. 13% new diagnosis left ventricular dysfunction echocardiography. Similarly, 27% right dysfunction. diastolic dimension 4.6 cm systolic dimension. 2% echo thrombus echocardiographic studies. PA pressure echocardiography 35 mmHg E/A ratio 1.2. 17% have pericardial effusion but none causing haemodynamic compromise. Conclusion This data suggests incidence recommend that should Conflict Interest References Zaim S, Chong JH, Sankaranarayanan V, Harky A. Multiorgan Response. Curr Probl Cardiol 2020;45(8):100618. doi:10.1016/j.cpcardiol.2020.100618 Tomasz J Guzik, Saidi A Mohiddin, Anthony Dimarco, Vimal Patel, Kostas Savvatis, Federica M Marelli-Berg, Meena S Madhur, Maciej Tomaszewski, Pasquale Maffia, Fulvio D’Acquisto, Stuart Nicklin, Ali Marian, Ryszard Nosalski, Eleanor C Murray, Bartlomiej et al. cardiovascular system: implications for risk assessment, diagnosis, treatment options. Cardiovascular Research, 1 August 2020;116(10):1666–1687